Delish Mexican Casserole with White Sauce
This casserole is my kind of comfort: layers of seasoned meat and beans (or veggies if you’re being virtuous), folded into soft tortillas and smothered with a creamy, tangy white sauce that somehow makes leftovers taste like a party. It’s easy enough for a weeknight, indulgent enough for a Sunday when you actually wear pants, and forgiving when you throw in whatever you have on hand.
My husband calls it “the magic pan” because he insists it disappears faster than anything I make. The kids love picking out their own cheese-studded bites, and I love that it reheats like a dream. We started making it back when I was too tired to think about dinner after work—now it’s our go-to when we want cozy without drama. Once I accidentally used sour cream instead of plain yogurt and, wild surprise, the entire family declared it a “genius upgrade.” I still sneak sour cream in sometimes.
Why You’ll Love This Delish Mexican Casserole with White Sauce
– It’s basically a layered hug: melty cheese, saucy filling, creamy top — all in one pan.
– Very forgiving: swap proteins, use leftover rice, or skip the tortillas for a lower-carb version.
– Feeds a crowd and leftovers are next-day gold — even cold if you’re into that sort of thing.
– Kid-friendly but sophisticated enough for guests; nobody has to choose between tacos and lasagna.

Kitchen Talk
This one has taught me humility. I burned the bottom layer once because I flirted with a phone call mid-bake; the smoky layer became “crunch” and the kids declared it “interesting.” I also learned that building the casserole a little wetter than you think helps the tortillas soften up instead of going chewy. Oh, and the white sauce? Don’t overboil it — keep it gentle and it stays silky. I’ve swapped ground turkey for beef, canned corn for frozen, and once I shredded rotisserie chicken straight into the skillet when I was hangry. No regrets.
Warm, creamy, and comforting — this Delish-style Mexican casserole with white sauce was an instant weeknight winner for our family. The sauce is rich without being heavy, the layers hold up well after baking, and a squeeze of lime and extra cilantro at the end brightened everything perfectly.
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Shopping Tips
– Protein: Ground beef, turkey, or shredded rotisserie chicken all work; pick whatever’s on sale or already in your fridge.
– Cheese: Go for a melty mix — Monterey Jack, cheddar, or a Mexican blend. Buy block cheese and shred it yourself for better melt and less waxy mystery.
– Canned Goods: Keep a can of diced tomatoes with green chiles and a can of beans (black or pinto) in the pantry; they’re the easiest flavor boosters here.
– Dairy: Sour cream or plain Greek yogurt makes the white sauce rich and tangy; choose full-fat for best texture, but low-fat works in a pinch.
– Spices: Cumin, chili powder, and smoked paprika are your friends — grab fresh jars if your current ones are sad and dusty.
– Fresh Herbs: A little cilantro brightens the whole casserole; buy a small bunch and use stems in the sauce if budget’s tight.
Prep Ahead Ideas
– Brown the meat (or cook the beans/veggies) a day ahead and store in an airtight container; flavors only get better overnight.
– Mix the white sauce in advance and refrigerate; gently reheat with a splash of milk to loosen before assembling.
– Shred cheeses and chop onions/peppers into separate containers — that five-minute assembly on a weeknight feels like magic.
– Store prepped layers in clear containers or one deep baking dish covered tightly with foil if assembling the next day.

Time-Saving Tricks
– Use rotisserie chicken or leftover taco meat to skip the pan-cooking step.
– No-cook white sauce option: blend Greek yogurt with a splash of milk and lime juice for a quick shortcut (skip boiling).
– Microwave tortillas briefly to make them pliable so the layers don’t crack while assembling.
– If you want crispy edges faster, broil the top for the last 2–3 minutes — watch it like a hawk.
Common Mistakes
– Over-saucing and ending up with a sloppy casserole — drain canned tomatoes or beans if they’re watery.
– I once layered cold sauce straight from the fridge and the dish never reached the right warm, melty state; warm components a bit before baking.
– Using pre-shredded cheese that resists melting — shred from a block for that beautiful ooze.
– Letting the casserole sit uncovered after baking can make the top tough; tent it with foil if you need to hold it.
What to Serve It With
– A crisp green salad with lime vinaigrette to cut the richness.
– Quick pickled red onions or a simple pico de gallo for brightness.
– Warm corn tortillas or crusty bread to scoop up the saucy bits.
– Charred street corn or a can of seasoned black beans for extra sides.
Tips & Mistakes
– Salt the filling as you cook — it’s harder to fix an under-seasoned casserole after baking.
– Use a slightly larger baking dish if you like crusty edges; a snug dish = more steam and softer top.
– If the top browns too quickly, cover loosely with foil and finish cooking.
– Oops fix: add a spoonful of cornstarch slurry to a too-thin sauce and simmer to thicken.
Storage Tips
Store leftovers in an airtight container in the fridge for 3–4 days. Reheat gently in the oven or microwave with a splash of milk to revive the sauce. Cold? Totally edible and sometimes oddly delicious for breakfast with an egg on top — no shame. Freeze in portions for up to 3 months; thaw overnight in the fridge before reheating.

Variations and Substitutions
– Swap ground beef for turkey, chicken, or crumbled tofu — I’ve done all three with good results.
– No-tortilla option: layer cooked rice or thin potato slices for a different texture.
– Dairy-free: use a cashew cream or full-fat coconut yogurt for the white sauce and a plant-based cheese.
– Add heat with chopped jalapeños or a swirl of chipotle in adobo when you want a smoky kick.
– Kid-friendly tweak: omit the chiles and add a touch of honey to the white sauce to make it milder.
Frequently Asked Questions

Delish Mexican Casserole with White Sauce
Ingredients
Main Ingredients
- 24 oz cooked shredded chicken rotisserie works great
- 4 tbsp unsalted butter
- 1 cup yellow onion, finely diced
- 2 tsp minced garlic
- 3 tbsp all-purpose flour
- 2 cup low-sodium chicken broth warm
- 1.5 cup sour cream full-fat preferred
- 4 oz diced green chiles, drained
- 1.5 tsp ground cumin
- 1 tsp chili powder
- 1.25 tsp kosher salt to taste
- 0.5 tsp black pepper
- 1 tbsp fresh lime juice
- 12 oz flour tortillas, cut into strips 6-inch tortillas
- 1 cup frozen corn, thawed or canned, drained
- 1 cup black beans, rinsed and drained optional
- 8 oz Monterey Jack cheese, shredded
- 4 oz cheddar cheese, shredded
- 0.25 cup fresh cilantro, chopped for garnish
Instructions
Preparation Steps
- Heat oven to 375°F. Lightly grease a 9x13-inch baking dish.
- Melt butter in a large saucepan over medium heat. Soften onion for 4–5 minutes; stir in garlic for 30 seconds.
- Sprinkle in flour and cook, stirring, for 1 minute to form a blond roux.
- Whisk in warm broth gradually. Simmer, whisking, until slightly thickened, 3–4 minutes.
- Remove from heat. Stir in sour cream, green chiles, cumin, chili powder, salt, pepper, and lime juice.
- Toss shredded chicken with about 1 cup of the white sauce; set aside.
- Spread 1/2 cup sauce in the dish. Layer half the tortilla strips, half the chicken, half the corn and beans, and one-third of the cheeses. Spoon over more sauce.
- Repeat layers with remaining tortillas, chicken, corn, and beans. Top with remaining sauce and the rest of the cheeses.
- Cover with foil and bake for 20 minutes. Uncover and bake 10–15 minutes more until bubbling and lightly browned.
- Rest 10 minutes before cutting. Sprinkle with cilantro and serve.
Notes
Featured Comments
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