Line a baking sheet with parchment paper. Preheat the oven to 410°F (210°C). Tip: For extra flakiness, place the stick of butter in the freezer for 10 minutes while you gather ingredients.
In a large bowl, whisk together the flour, sugar, baking powder, salt, lemon zest, and cardamom.
Using the large holes of a box grater, grate the cold butter directly into the dry mixture. Toss gently with your fingertips to coat the butter shreds so they’re evenly distributed and no large clumps remain.
In a measuring cup, whisk the cold heavy cream, egg, and vanilla. Pour over the flour mixture and stir with a fork until shaggy and just moistened. If very dry spots remain, drizzle in 1–2 teaspoons more cream.
Toss the blueberries with 1 teaspoon flour (to minimize purple streaking), then add them to the bowl and fold gently a few times to disperse without crushing.
Tip the dough onto a lightly floured sheet of parchment. Pat into a 6×8-inch rectangle about 1 inch thick. Fold the rectangle in thirds like a letter, rotate 90°, and pat into a 7-inch round. Slide the parchment onto the prepared baking sheet and refrigerate for 20 minutes.
Once chilled, cut the round into 8 wedges. Separate the wedges to leave about 2 inches of space. Brush tops lightly with a little cream (from the cup) for shine.
Bake for 16–20 minutes, until the edges are golden and the centers feel set when gently pressed. Cool on the pan for 10 minutes, then transfer to a rack.
For the glaze, whisk powdered sugar with 2 tablespoons lemon juice until smooth and drizzly. Add a few drops more juice if needed. Spoon or drizzle over warm scones and let set for 5 minutes before serving.