Stir cookie crumbs, melted butter, and a pinch of salt together. Press into a 9-inch pie plate.
Freeze the crust for 10 minutes to firm up while you make the filling.
Beat cream cheese and peanut butter until completely smooth and fluffy.
Mix in powdered sugar, vanilla, and a small pinch of salt until blended.
Whip the cold cream to soft peaks, then gently fold it into the peanut butter mixture.
Fold in half of the chopped peanut butter cups. Spread filling into the chilled crust and smooth the top.
Warm the ganache cream until steaming, then pour over chocolate chips. Rest 2 minutes, then stir silky smooth.
Cool ganache 5 minutes. Pour over the pie, then scatter remaining cups on top.
Drizzle with warmed peanut butter and sprinkle peanuts if using. Chill until set, at least 3 hours.