Preheat the air fryer to 375°F for 5 minutes. Lightly brush or spray the basket with olive oil.
In a bowl, combine ground beef, salt, black pepper, garlic powder, onion powder, and Worcestershire. Mix just until combined.
Divide the mixture into 4 equal portions. Form into 0.5-inch-thick patties slightly wider than the buns and press a small dimple in the center of each.
Place patties in a single layer in the basket (cook in batches if needed). Air fry at 375°F for 6 minutes.
Flip the patties and cook 4 to 6 minutes more, or until the internal temperature reaches 160°F.
Add a slice of cheese to each patty during the last 1 minute to melt.
Toast buns in the air fryer for 1 to 2 minutes if desired. Assemble burgers and serve immediately.
Notes
Use 80/20 beef for the juiciest burgers. Avoid overcrowding; cook in batches for best browning. For food safety, cook ground beef to 160°F. Leftovers keep up to 3 days refrigerated.