Pick through the crabmeat for shells, then blot it dry with paper towels.
Whisk mayonnaise, Dijon, Worcestershire, lemon juice, Old Bay, hot sauce, salt, and pepper in a large bowl.
Whisk in the beaten egg until smooth to form the binder.
Fold in the crab, parsley, and scallions, keeping the lumps intact.
Scatter the panko over the mixture and gently fold until it just holds together.
Chill the mixture 15–20 minutes to firm up for easier shaping.
Form eight patties about 3 inches wide and 3/4 inch thick; press lightly so they hold.
Heat butter and oil in a large skillet over medium heat until shimmering.
Cook cakes 3–4 minutes per side until deep golden and heated through; work in batches if needed.
Rest 2 minutes on a rack. Serve hot with lemon wedges or your favorite sauce.