Drain tuna well, then flake it with a fork and set aside.
Whisk mayonnaise, beaten egg, lime juice, cumin, salt, and pepper in a large bowl.
Stir in jalapeño, cilantro, red onion, garlic, and lime zest until evenly combined.
Fold in tuna and 2/3 cup panko. Let the mixture rest 5 minutes to hydrate.
Scoop and shape the mixture into 8 small patties. Lightly coat each with the extra panko.
Heat olive oil in a large skillet over medium heat. Cook patties 3–4 minutes per side until crisp and golden.
Transfer to a paper towel–lined plate. Serve hot with lime wedges or your favorite creamy sauce.