In a large bowl, combine the ground beef, breadcrumbs, milk, eggs, onion, Worcestershire sauce, salt, and pepper. Mix until well combined, but do not overmix.
Press the mixture into a loaf pan or shape into a loaf on a baking sheet lined with parchment paper.
In a separate small bowl, mix together the brown sugar and ketchup. Spread evenly over the top of the meatloaf.
Bake in the preheated oven for 60 minutes, or until the meat is no longer pink and juices run clear.
Let the meatloaf rest for 10 minutes before slicing and serving.
Notes
For extra flavor, consider adding minced garlic or bell peppers to the meat mixture.